Cell Culture Growth Factors and Hormones
ABclonal Technology FGFR3 Rabbit pAb
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.
Medchemexpress LLC CD70 Rat HEK293 F 10ug
CD70 is the ligand of CD27 in activated T and B lymphocytes is an important cytokine in CD70-CD27 pathway involving with the generation and maintenance of T cell immunity[1] CD70 is a surface antigen also shows antiviral activity and regulates viability of tumor cells and regulatory T cells[2][3] As for CD70 protein in rat contains TNF 2 domain (57-188 a a) and transmembrane helix belonging to the tumor necrosis factor (TNF) family CD70 Protein Rat (HEK293 Fc) is 150 amino acids in length (Q46-P195) and is expressed in the HEK293 cells with N terminal hFc-tag
Medchemexpress LLC CD45 Mouse HEK293 5ug
The CD45 protein is a multifunctional member of the protein tyrosine phosphatase family with heparan sulfate proteoglycan and heparin binding activity as well as protein tyrosine phosphatase activity It plays a crucial role in lymphocyte differentiation macromolecular metabolic processes and signal transduction regulation CD45 Protein Mouse (HEK293 Fc) is the recombinant mouse-derived CD45 protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC CD5 Human HEK293 100ug
The CD5 protein is a potential receptor that regulates T cell proliferation Its interactions with CD72/LYB-2 and PTPN6/SHP-1 indicate multifaceted roles in cellular processes serving as key mediators of T cell responses CD5 Protein Human (HEK293 His) is the recombinant human-derived CD5 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC EGF Human HEK293 50ug
The Progranulin/PGRN protein is involved in a variety of cellular processes including cell growth inflammation and neurodegeneration It acts as a regulator of tissue repair and has been implicated in the pathogenesis of several diseases including Alzheimer s disease and frontotemporal dementia Progranulin/PGRN interacts with various receptors and signaling pathways to exert its effects on cellular function and disease progression EGF Protein Human (HEK293 N-hFc solution) is the recombinant human-derived EGF protein expressed by HEK293 with N-hFc labeled tag
Medchemexpress LLC PLGF Human HEK293 10ug
Recombinant human PLGF-2 produced in HEK293 cells with a polyhistidine tag, suitable for research on angiogenesis and endothelial cell biology. The protein is active as a disulfide-linked homodimer, interacts with VEGFR-1/FLT1 and neuropilins, and is supplied with endotoxin control; follow the manufacturer datasheet for reconstitution and handling instructions.
- Expressed in HEK293 cells for human-like post-translational modifications.
- Includes a His affinity tag to facilitate purification and detection.
- Active as a disulfide-linked homodimer that interacts with VEGFR-1 and neuropilins.
- Low endotoxin level suitable for cell-based assays.
- Stable when stored frozen; aliquot after reconstitution to preserve activity.
Medchemexpress LLC FGF-2 Mouse 145a.a 500ug
Recombinant mouse FGF-2 (145 amino acids) is a tag-free, lyophilized growth factor produced in E. coli and supplied as a 500 μg vial. It activates FGFR-mediated signaling to promote cell proliferation, angiogenesis, and cartilage and bone repair, and is provided at >95% purity for research applications.
- Contains 145 amino acids, predicted mass 16.3 kDa.
- Produced in E. coli and presented tag free.
- Lyophilized from PBS (pH 7.4) for stability.
- Purity greater than 95% by reducing SDS-PAGE.
- Supplied as a 500 μg amount for experimental use.
- Store at -20°C; reconstituted material stable at 4°C for 1 week.
Medchemexpress LLC PDGF-BB Human His 2ug
Recombinant human PDGF-BB (His) is a lyophilized, N-terminal 6xHis-tagged growth factor expressed in E. coli and provided for research use in studies of cell signaling, proliferation, migration, and tissue regeneration. The protein is supplied with low endotoxin and high purity to support sensitive cell-based assays.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg) suitable for cell assays.
- Contains the mature sequence region S82-T190 with an N-terminal His tag.
- Lyophilized formulation for extended shelf life and convenient storage.
- Formulated with buffer components to enhance stability on reconstitution.
Medchemexpress LLC FGF-19 Human His 10ug
Recombinant human FGF-19 (His-tagged) is a research-grade growth factor used to investigate FGF-19-dependent signaling and metabolic regulation. The protein is produced in E. coli and is applied in biochemical and cell-based studies probing bile acid metabolism and glucose homeostasis.
- Recombinant human protein suitable for biochemical and cell-based assays.
- Expressed in E. coli with an N-terminal 6xHis tag for straightforward purification.
- Regulates bile acid biosynthesis by inhibiting CYP7A1 expression.
- Positively regulates JNK and ERK1/2 signaling pathways.
- Stimulates adipocyte glucose uptake via KLB and FGFR4-dependent mechanisms.
- Supplied in small research pack sizes (e.g., 10 μg) for experimental use.
Medchemexpress LLC RBP4 Human HEK293 50ug
Recombinant human retinol-binding protein 4 (RBP4) produced in HEK293 cells with a C-terminal 6xHis tag. Supplied as a 50 μg vial for research use, this purified protein is suitable for biochemical assays, antibody validation, and immunodetection applications; follow the product datasheet for storage and handling recommendations.
- Expressed in HEK293 cells to preserve human-like post-translational modifications.
- C-terminal 6xHis tag facilitates detection and purification.
- Purified recombinant protein suitable for biochemical assays and antibody validation.
- Supplied as a 50 μg vial for small-scale experiments; store and handle per recommendations.
Medchemexpress LLC RBP4 Human HEK293 100ug
Recombinant human retinol-binding protein 4 (RBP4) expressed in HEK293 cells with a C-terminal 6xHis tag. Supplied lyophilized and purified to >95% by reducing SDS-PAGE, this protein is provided in multiple pack sizes, including a 100 μg option, for research applications. Formulated in 20 mM phosphate buffer, 150 mM NaCl, pH 7.8; store at -20°C and aliquot for long-term storage at -80°C.
- Expressed in HEK293 cells for mammalian post-translational modifications.
- C-terminal 6xHis tag enables affinity purification and detection.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Lyophilized formulation for improved stability and convenient storage.
- Available in multiple sizes, including a 100 μg pack.
- Contains amino acids E19-L201; approximate molecular weight ~21 kDa.
- Intended for research use only.
Medchemexpress LLC FGF-12 Human 181a. 50ug
Recombinant human FGF-12 (181 amino acids) is a His-tagged protein expressed in E. coli, supplied lyophilized and characterized for high purity, low endotoxin, and verified biological activity. It is intended for in vitro signaling and functional studies involving neuronal excitability and regulation of voltage-gated sodium channels.
- Highly pure protein (>95% by reducing SDS-PAGE).
- Low endotoxin level (<1 EU/μg) suitable for cell-based assays.
- Biologically active with ED50 ≈1.7 ng/mL in a standard proliferation assay.
- Lyophilized from a buffered formulation to enhance stability.
- N-terminal 6xHis tag enables straightforward purification and detection.
- Stable when stored lyophilized at -20°C; aliquot and freeze after reconstitution for long-term storage.
Medchemexpress LLC HY-P7198 10ug Medchemexpress, I-309/CCL1 (CHO-expressed), Human CAS: Purity:>98%
Medchemexpress, HY-116282B 100mg Dextran sulfate sodium salt (MW 16000-24000) CAS:9011-18-1 Dextran sulfate sodium salt (MW 16000-24000) is a is a polymer of anhydroglucose with the molecular weight range of 16000-24000. Dextran sulfate sodium salt inhibits the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC M-CSF Human HEK293 100ug
The M-CSF protein is an important cytokine that modulates hematopoietic precursor cells especially mononuclear phagocytes affecting innate immunity and inflammation through the release of proinflammatory chemokines It is essential for osteoclast proliferation and regulates bone resorption bone development and fertility M-CSF Protein Human (HEK293 His) is the recombinant human-derived M-CSF protein expressed by HEK293 with C-10 His labeled tag